Paleo Diets Fight Inflammation

According to recent research studies a Paleo diet can reduce inflammation, heal intestinal inflammation, and help prevent heart disease by increasing Interlukin-10. Other studies on both humans and mice show just how important this anti-inflammatory cytokine can be.

Defects in the Interlukin-10 have been linked to Inflammatory Bowel Disease and other intestinal inflammation issues. Inflammation is one of the main causes of gut pain and is implicated in “leaky gut” (permeable intestine).
“study participants experienced a 35 percent increase in levels of interlukin-10 (IL-10)… Scientist think that high IL-10 levels may counteract inflammation, providing a protective effect for blood vessels… increase in IL-10 could suggest a lower risk for cardiovascular disease after following the Paleo diet… The researchers also observed changes in other biomarkers of inflammation” — American Physiological Society (APS)
It has been known for sometime that IL-10 and IL-10 receptors play a part in Inflammatory Bowel Diseases.
“Like other primary immunodeficiencies, IL-10 and IL-10 receptor (IL10R) deficiency present with IBD and demonstrate the sensitivity of the intestine to any changes of the immune system. ” — PubMed #22890722
IL-10 also modulates the body’s immune response to intestinal infections helping to prevent excessive and chronic inflammatory responses.
“Interleukin-10 (IL-10) curtails immune responses to microbial infection and autoantigens and contributes to intestinal immune homeostasis… Interleukin-10 (IL-10) is a potent anti-inflammatory cytokine essential for protecting the host against excessive inflammatory and immune responses… The importance of IL-10 in immune homeostasis has been demonstrated in mice and humans.” — American Society for Microbiology

“Interleukin 10 receptor signaling: master regulator of intestinal mucosal homeostasis in mice and humans… Interleukin 10 (IL10) is a key anti-inflammatory cytokine that can inhibit proinflammatory responses of both innate and adaptive immune cells. An association between IL10 and intestinal mucosal homeostasis became clear with the discovery that IL10 and IL10 receptor” — PubMed #24507158

The Gut Health Protocol recommends its own modified Paleo diet; the diet is specific to helping the body fight the infection, heal the gut, and fight inflammation.

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